mana2 student pon, rasanya biasa la kalau buat assignment last2 minit. kan? assignment aku ni diberi masa awal sem dan dijangkan perlu dihabiskan hujung minggu ni. tapi minggu lepas baru aku mula buat. 

bak kata member aku, "last minute work always work". hehehe... papepon, dah alang2 aku dah buat, aku nak tempek la kat sini, ade gak pek-dah pembaca2 blog aku. boleh tambah ilmu.

assignment ni memerlukan kami buat laman web pasai "malaria". part aku bahagian intro dan beberapa bahagian lagi. so, sapa yang nak tau sikit2 pasai malaria, boleh layan kat bawah ni:

Malaria is a climate sensitive disease[1] and has become an important cause of death and illness in children and adults, especially in tropical countries.[2] It is caused by a parasite called Plasmodium, which is transmitted via the bites of infected mosquitoes. In the human body, the parasites multiply in the liver, and then infect red blood cells.[3]

there is four different Plasmodium that can cause disease in humans[4] which are:
1.      Plasmodium falciparum
2.      Plasmodium malariae
3.      Plasmodium ovale
4.      Plasmodium vivax. 

These parasites are transmitted from person to person by female Anopheles mosquitoes throughout tropical and subtropical regions throughout the world[5] and can be contracted by shared needles, blood transfusions or transplacenta infections.[6]

The species of the mosquitoes are include Anopholes freeborni, Anopholes hermsi and Anopholes puntipennis[6] 

When the infected mosquito bites, it inject plasmodium sporozoites into the bloodstream. This sporozoites migrate through the blood to the liver. In the liver, they form cyst-like structure containing thousands of merozoites. Upon release, each merozoites invades a red blood cell (RBC) and becoming a trophozoite. This trophozoites used the haemoglobin in the RBC as their nutrient.[7]

The trophozoites multiply and become merozoites. Eventually, the RBC will ruptures and release the merozoites. Some of this merozoites can enter another RBC to repeat the cycle and some of them become the gametocytes which be picked up by the female mosquito.

In the mosquito, the gemetocytes undergo the sexual cycle to form the sporozoites that will be used to infect another human.[7]

Malaria has taking the lives of almost one million people a year, most of them in sub-Saharan Africa and under the age of 5.[8] It is the fifth leading cause of death worldwide and almost half the world’s population (3.3 billion)[8] is at risk.

The effectiveness of a drug treatment is related to the particular species of infecting plasmodium and the stage of its life cycle that is targeted.[7]

In many warm, tropical areas of the world, it is endemic.  Although its range has diminished, the global warming has threatens to expand it once again.[9]

references :

2.      WHO Guidelines for the treatment of malaria, second edition
5.      Surveillance and control of diseases spread by mosquitoes and ticks in Florida. HRS Pamphlet HRSP 150-12, 1992
7.      Harvey R.A, Champe P.C.(2009) Lippincott’s illustrated reviews : Pharmacology 4th edition, 421.
8.      World malaria report 2010, WHO

untuk maklumat lanjut, sila layari laman web kami di :